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KMID : 1137820150360050198
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의공학회지
2015 Volume.36 No. 5 p.198 ~ p.203
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Estimation of Cardiac Pumping Performance according to the Ventricular Electrical Activation Time Distribution by Using Physiome Model
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Kim Hyeong-Gyun
Lim Ki-Moo
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Abstract
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The purpose of the study is to examine the effects of pacemaker location on cardiac pumping efficacy theoretically. We used a three-dimensional finite element cardiac electromechanical model of canine ventricles with models of the circulatory system. Electrical activation time for normal sinus rhythm and artificial pacing in apex, left ventricular free wall, and right ventricular free wall were obtained from electrophysiological model. We applied the electrical activation time maps to the mechanical contraction model and obtained cardiac mechanical responses such as myocardial contractile ATP consumption, stroke work, stroke volume, ejection fraction, and etc. Among three artificial pacing methods, left ventricle pacing showed best performance in ventricular pumping efficacy.
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KEYWORD
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Cardiac electromechanical model, Electrical activation time, ATP consumption rate, Stroke work, Stroke volume
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